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Table 1 Determination of 4Ā F-PCC dosage for reversal of coagulopathy

From: Evaluation and treatment of gastrointestinal bleeding in patients taking anticoagulants presenting to the emergency department

Pretreatment INR

2 to < 4

4 to 6

> 6

Dose of 4Ā F-PCC (KcentraĀ®)

[units/kg]

25

35

50

Maximum dose [units]

2500

3500

5000