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Table 2 Determination of dosing of Andexanet alfa

From: Evaluation and treatment of gastrointestinal bleeding in patients taking anticoagulants presenting to the emergency department

FXa Inhibitor

Strength of the last dose

Time from the last dose

< 8Ā h/ unknown

≄ 8Ā h

Rivaroxaban

≤ 10Ā mg

Low dose

Low dose

> 10Ā mg/ unknown

High dose

Apixaban

≤ 5Ā mg

Low dose

Low dose

> 5Ā mg/unknown

High dose