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Table 7 Frequency distribution of in-hospital mortality adjusted by age, gender, SOFA score, SAPS III, detectability of epinephrine, levels of epinephrine, mechanical ventilation and use of vasoactive drugs

From: Catecholamine concentration as a predictor of mortality in emergency surgical patients

 

In-hospital mortality

All

p-value*

OR (95% CI)

Yes

No

n (%)

n (%)

Age

      
 

≤ 60

10 (20.8)

38 (79.2)

48 (53.3)

0.01

1.00 (Reference)

 

> 60

20 (47.6)

22 (52.4)

42 (46.7)

 

3.45 (1.37; 8.70)

Gender

      
 

Male

17 (27.4)

45 (72.6)

62 (68.9)

0.09

1.00 (Reference)

 

Female

13 (46.4)

15 (53.6)

28 (31.1)

 

2.29 (0.91; 5.81)

SOFA score

      
 

1 (< 9)

12 (21.4)

44 (78.6)

56 (62.2)

< 0.01

1.00 (Reference)

 

2 (9–11)

9 (52.9)

8 (47.1)

17 (18.9)

 

4.13 (1.31; 12.98)

 

3 (> 12)

9 (52.9)

8 (47.1)

17 (18.9)

 

4.13 (1.31; 12.98)

Epinephrine

      
 

1 (Detectable)

9 (30.0)

21 (70.0)

30 (33.3)

0.81

1.00 (Reference)

 

0 (Undetectable)

21 (35.0)

39 (65.0)

60 (66.7)

 

1.26 (0.49; 3.23)

Norepinephrine

      
 

1 (< 2006.5)

8 (20.5)

31 (79.5)

39 (43.3)

0.02

1.00 (Reference)

 

2 (≥ 2006.5)

22 (43.1)

29 (56.9)

51 (56.7)

 

2.94 (1.13; 7.64)

Glasgow

      
 

1 (3–8)

22 (43.1)

29 (56.9)

51 (56.7)

< 0.01

5.12 (1.56; 16.78)

 

2 (9–12)

4 (50.0)

4 (50.0)

8 (8.9)

 

6.75 (1.19; 38.40)

 

3 (13–15)

4 (12.9)

27 (87.1)

31 (34.4)

 

1.00 (Reference)

SAPS III

      
 

1 (17–41)

2 (9.1)

20 (90.9)

22 (24.5)

< 0.01

1.00 Reference

 

2 (42–52)

4 (19.0)

17 (80.9)

21 (23.3)

 

2.35 (0.38; 14.47)

 

3 (53–63)

10 (47.6)

11 (52.4)

21 (23.3)

 

9.09 (1.68; 49.12)

 

4 (64–103)

14 (53.8)

12 (46.2)

26 (28.9)

 

11.67 (2.25; 60.47)

Mechanical Ventilation

      
 

0 (yes)

26 (43.3)

34 (56.7)

60 (66.7)

< 0.01

4.97 (1.54; 16.01)

 

1 (no)

4 (13.3)

26 (86.7)

30 (33.3)

 

1.00 Reference

Vasoactive drugs

      
 

0 (yes)

24 (80.0)

31 (51.7)

55 (61.1)

0.01

1.00 Reference

 

1 (no)

6 (20.0)

29 (48.3)

35 (38.9)

 

3.74 (1.34; 10.46)

Lactate

      
 

1 (normal)

22 (75.9)

49 (84.5)

71 (81.6)

0.23

1.00 Reference

 

2 (moderately elevated)

2 (6.9)

6 (10.3)

8 (9.2)

 

1.35 (0.25; 7.21)

 

3 (severely elevated)

5 (17.2)

3 (5.2)

8 (9.2)

 

0.27 (0.06; 1.23)

  1. OR odds ratio; 95% CI 95% confidence interval
  2. *Fisher’s exact test