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Table 3 Cox regression analysis of the variables

From: U-shaped correlation of lymphocyte count with all-cause hospital mortality in sepsis and septic shock patients: a MIMIC-IV and eICU-CRD database study

Variables

Univariable

Multivariable

HR

95% CI

P value

HR

95% CI

P value

Age

1.03

1.02- 1.03

 < 0.001

1.03

1.02- 1.03

 < 0.001

Lymphocytes

1.04

1.02- 1.07

 < 0.001

1.06

1.03–1.08

 < 0.001

WBC

1.02

1.01- 1.02

 < 0.001

1.01

1.02- 1.02

 < 0.001

Neutrophils

1.03

1.02- 1.03

 < 0.001

   

Monocytes

1.32

1.28–1.36

 < 0.001

   

Platelet

1.00

1.00- 1.00

0.006

   

Hemoglobin

1.01

1.0- 1.02

0.28

   

Albumin

0.68

0.66- 0.71

 < 0.001

0.76

0.73–0.79

 < 0.001

Bun

1.01

1.01- 1.01

 < 0.001

   

Calcium

1.02

0.98- 1.05

0.29

   

Creatinine

1.10

1.08- 1.12

 < 0.001

1.02

1.0–1.04

0.011

Glucose

1.00

1.00- 1.00

 < 0.001

   

Sodium

1.01

1.01- 1.02

 < 0.001

   

Potassium

1.21

1.17- 1.25

 < 0.001

1.06

1.03–1.1

 < 0.001

ALT

1.00

1.00- 1.00

 < 0.001

   

AST

1.00

1.00- 1.00

 < 0.001

   

Heart rate

1.01

1.01- 1.01

 < 0.001

   

Systolic blood pressure

1.00

1.00- 1.00

0.013

   

Diastolic blood pressure

1.00

1.00- 1.00

 < 0.001

   

Mean blood pressure

1.01

1.01- 1.01

 < 0.001

   

Respiratory Rate

1.03

1.02- 1.03

 < 0.001

1.03

1.02–1.03

 < 0.001

Temperature

0.85

0.82- 0.88

 < 0.001

0.86

0.83–0.89

 < 0.001

Spo2

0.99

0.96- 1.02

0.42

   

First day sofa

1.13

1.13- 1.14

 < 0.001

1.13

1.13–1.14

 < 0.001

Gender

 Female

   Male

0.89

0.85- 0.94

 < 0.001

0.92

0.87- 0.97

0.003

  1. WBC White Blood count, ALT alanine aminotransferase, AST aspartate aminotransferase