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Table 2 Univariable and multivariable logistic regression analyses of the effects of elevated initial serum lactate levels (iSL) on morbidity and in-hospital mortality among trauma patients admitted to the Puerto Rico Trauma Hospital (July 2014 – June 2019) ±

From: Examining the association of elevated initial serum lactate with mortality and morbidity in trauma patients: a retrospective study

Characteristics

OR (95%CI) a

p-value

AOR (95%CI) a

p-value

TICU Admissionb

  

(N = 511)

 

 Elevated iSL levels (mg/dL)

2.06 (1.46–2.92) *

< 0.001 *

1.11 (0.71–1.75)

0.65

Need of Mechanical Ventilationc

  

(N = 412)

 

 Elevated iSL levels (mg/dL)

2.80 (1.97–3.98) *

< 0.001 *

1.49 (0.89–2.49)

0.13

In-hospital mortalityd

  

(N = 511)

 

 Elevated iSL levels (mg/dL)

2.18 (1.36–3.51) *

< 0.001 *

1.72 (0.97–3.04)

0.06

  1. TICU: Trauma Intensive Care Unit; OR: Odds Ratio; CI: Confidence Interval; AOR: Adjusted Odds Ratio; iSL: initial serum lactate; a reference category is normal initial serum lactate levels (mg/dL); b adjusted for sex, age, mechanism of injury, injury severity score, Glasgow coma scale, systolic blood pressure, respiratory and heart rates, creatinine, and albumin; c adjusted for age, mechanism of injury, injury severity score, Glasgow coma scale, systolic blood pressure, respiratory and heart rates, creatinine, and albumin; d adjusted for age, mechanism of injury, injury severity score, Glasgow coma scale, systolic blood pressure, respiratory and heart rates, creatinine, and albumin. *Statistically significant when the confidence interval does not include 1.00 and p value < 0.05. ±Study population had missing data; therefore, the N was decreased