Fig. 2

The histopathological findings. A – Fragment of jejunum with edematous mucosa and neutrophilic inflammatory infiltrates. Desquamation of the epithelium with a tendency toward erosive changes, signs of active crypt epithelial regeneration, and occasional crypt abscesses are observed (acute bacterial enteritis). B – Lung tissue with thickened interalveolar septa and mononuclear inflammatory infiltrates with admixture of neutrophils. The alveolar epithelium is flattened and damaged; numerous hyaline membranes are observed. Occasional alveolar spaces contain exudate. Vascular congestion and microthrombosis (pneumonia-associated diffuse alveolar damage). C – Adrenal gland with massive extravasation of erythrocytes (hemorrhage) into the cortical and medullary regions, causing disruption of the gland’s histoarchitecture. Microloci of coagulative necrosis with loss of cellular borders and karyolysis. Microloci of inflammatory reaction zones (Waterhouse-Friderichsen syndrome). D – Renal medulla with mostly preserved histoarchitecture. Foci of tubules show necrotic and apoptotic epithelial changes. Numerous vessels exhibit signs of stasis and thrombosis, with single perivascular inflammatory cells present (focal acute tubular necrosis of renal tubular epithelium, signs of thrombovasculitis)