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Table 2 Results of laboratory tests

From: A retrospective study to predict failure of high-flow oxygen therapy for acute hypoxic respiratory failure

 

All Patients (n = 388) Mean ± SD

HFNC Success Group (n = 256) Mean ± SD

HFNC Failure Group (n = 132) Mean ± SD

reference value

p

WBC (*109/L)

10.14 ± 6.140

10.57 ± 6.561

9.294 ± 5.218

3.5–9.5

0.335

N (%)

85.57 ± 13.16

85.41 ± 14.22

85.93 ± 10.66

40–75

0.864

CRP (mg/L)

94.43 ± 83.63

83.31 ± 87.62

116.3 ± 71.46

0–10

0.029

PCT (ng/mL)

3.639 ± 10.50

3.745 ± 12.14

3.430 ± 6.311

 < 0.5

0.893

L (%)

8.666 ± 10.05

9.520 ± 11.99

7.039 ± 4.214

20–50

0.268

ESR (mm/h)

57.00 ± 35.72

56.74 ± 33.58

57.47 ± 40.52

0–20

0.951

Hb (g/L)

111.98 ± 26.44

114.44 ± 26.85

107.21 ± 25.32

130–175

0.204

PLT (*109/L)

193.14 ± 97.10

211.86 ± 100.9

156.85 ± 78.62

125–350

0.008

Lac (mmol/L)

3.240 ± 3.471

3.072 ± 2.877

3.631 ± 4.649

0.5–1.7

0.572

PT (s)

15.37 ± 13.91

15.43 ± 16.95

15.26 ± 4.853

10–13

0.954

INR

1.314 ± 1.223

1.317 ± 1.488

1.307 ± 0.441

0.5–1.2

0.971

TT (s)

15.87 ± 2.096

15.73 ± 1.345

16.15 ± 3.042

14–21

0.359

APTT (s)

31.06 ± 8.879

30.06 ± 6.954

32.91 ± 11.53

25–31.3

0.138

Fib (mg/dL)

498.67 ± 220.30

495.03 ± 234.84

505.40 ± 193.83

200–400

0.829

D-Dimer (mg/L)

6.495 ± 10.33

5.135 ± 9.412

9.010 ± 11.58

0–0.8

0.033

TNFa (pg/mL)

28.70 ± 107.2

15.99 ± 18.58

55.48 ± 186.5

 < 8.1

0.109

IL-1b (pg/mL)

16.55 ± 67.13

9.707 ± 14.02

30.47 ± 115.3

 < 5.0

0.174

IL-2 (pg/mL)

1420.57 ± 1459.25

1237.29 ± 1182.11

1806.79 ± 1884.86

223–710

0.089

IL-6 (pg/mL)

99.97 ± 230.45

69.64 ± 189.90

159.61 ± 288.94

 < 3.4

0.082

IL-8 (pg/mL)

148.83 ± 801.16

47.83 ± 67.77

361.64 ± 1401.90

 < 6.2

0.088

IL-10 (pg/mL)

36.59 ± 150.47

11.84 ± 21.87

88.73 ± 258.72

 < 9.1

0.025

TB (umol/L)

13.57 ± 12.18

11.49 ± 9.256

17.53 ± 15.80

3.4–20.4

0.02

CB (umol/L)

5.981 ± 8.658

4.184 ± 3.825

9.412 ± 13.25

0–6.8

0.004

ALT (U/L)

123.90 ± 433.43

127.97 ± 451.23

116.12 ± 403.89

9–50

0.9

AST (U/L)

177.43 ± 761.73

216.56 ± 921.74

102.73 ± 260.21

15–40

0.49

LDH (U/L)

606.47 ± 1143.30

633.97 ± 1375.09

554.82 ± 480.66

109–245

0.75

Albumin (g/L)

32.79 ± 4.864

33.76 ± 4.848

30.94 ± 4.394

35–55

0.006

Creatinine(umol/L)

153.37 ± 203.33

148.38 ± 209.46

162.61 ± 194.31

44–115

0.748

Urea(umol/L)

12.52 ± 10.75

11.24 ± 9.431

14.89 ± 12.66

2.9–8.2

0.117

cTNT (ng/mL)

0.0688 ± 0.181

0.0798 ± 0.2207

0.048 ± 0.0431

 < 0.014

0.424

proBNP(pg/mL)

3730.02 ± 7059.32

3502.83 ± 6590.11

4163.12 ± 7971.34

1–100

0.671

  1. Abbreviations: HFNC high-flow nasal cannula, SD standard deviation, WBC white blood cell, N(%) Neutriphil percentage, CRP C-reactive protein, PCT procalcitonin, L(%) lymphocyte percentage, ESR Erythrocyte sedimentation rate, Hb hemoglobin, PLT platelet, Lac Lactic acid, INR international normalized ratio, TT thrombin time, PT prothrombin time, APTT activated partial thromboplastin time, Fib fibrinogen, TNFα tumor necrosis factor, IL-1β interleukin β, IL-6 interleukin 6, IL-8 interleukin 8, IL-10 interleukin-10, TB total bilirubin, CB conjuged bilirubin, ALT alanine transaminase, AST aspartate transaminase, LDH lactate dehydrogenase, cTnT cardiac troponin T, proBNP pro brain natriuretic peptide
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International Journal of Emergency Medicine

ISSN: 1865-1380

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